STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR_A0214Trp repressor binding protein WrbA, putative; Similar to GB:M99166 SP:P30849 PID:148264 GB:U00096 PID:1651499 percent identity: 54.36; identified by sequence similarity; putative; Belongs to the WrbA family. (200 aa)    
Predicted Functional Partners:
DR_0011
Conserved hypothetical protein; Similar to GB:U14003 SP:P39315 PID:537052 GB:U00096 PID:1790656 percent identity: 71.94; identified by sequence similarity; putative.
  
 
  0.902
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
    
  0.900
dps1
DNA-binding stress response protein, Dps family; Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). Both oligomeric forms of dps exhibit ferroxidase activity and DNA binding. Dodecameric dps is capable of Fe(2+) oxidation/mineralization. Only dimeric dps affords efficient DNA protection against hydroxyl radical-mediated cleavage.
  
  
 0.582
DR_2251
Hypothetical protein; Identified by Glimmer2; putative.
   
  
 0.579
DR_A0202
Superoxide dismutase (sodC), Cu-Zn family; Similar to SP:P15453 percent identity: 54.55; identified by sequence similarity; putative.
 
 
 0.546
DR_0888
Hypothetical protein; Identified by Glimmer2; putative.
   
  
 0.529
DR_1591
Hypothetical protein; Identified by Glimmer2; putative.
 
    0.458
DR_A0216
Esterase, putative; Similar to GB:U00096 PID:1788770 PID:1799860 PID:1799864 percent identity: 54.32; identified by sequence similarity; putative.
  
    0.445
DR_A0215
Hypothetical protein; Identified by Glimmer2; putative.
       0.439
DR_2256
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
  
 0.427
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.