STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynUKynureninase, putative; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (462 aa)    
Predicted Functional Partners:
kynA
Tryptophan 2,3-dioxygenase, putative; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.999
DR_A0340
Conserved hypothetical protein; Similar to PID:1086620 percent identity: 47.80; identified by sequence similarity; putative.
 
 0.988
katA
Catalase; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.
   
 
  0.903
DR_A0259
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 
  0.903
DR_1271
Conserved hypothetical protein; Similar to PID:2193927 GB:AL123456 percent identity: 48.88; identified by sequence similarity; putative.
   
  
 0.597
DR_1160
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
  
  
 0.557
hutH
Histidine ammonia-lyase; Similar to GB:M20659 SP:P10944 GB:D31856 PID:143076 PID:603770 percent identity: 68.00; identified by sequence similarity; putative; Belongs to the PAL/histidase family.
   
  
 0.528
DR_A0328
Oxidoreductase, putative; Similar to GB:AL009126 percent identity: 47.42; identified by sequence similarity; putative.
  
  
 0.509
DR_1843
Peptide ABC transporter, putative; Similar to SP:P26902 PID:48804 GB:AL009126 percent identity: 53.31; identified by sequence similarity; putative.
  
   
 0.470
DR_A0337
glutaryl-CoA dehydrogenase; Similar to GB:AE000782 percent identity: 68.44; identified by sequence similarity; putative.
  
  
 0.469
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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