STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aldAAldehyde dehydrogenase; Similar to GB:M74003 SP:P46368 PID:141886 percent identity: 88.82; identified by sequence similarity; putative. (515 aa)    
Predicted Functional Partners:
DR_0814
Proline dehydrogenase, putative; Converts proline to delta-1-pyrroline-5-carboxylate.
 
 
 0.955
DR_0460
acetyl-CoA synthase; Similar to PID:1001216 PID:1001254 percent identity: 62.90; identified by sequence similarity; putative.
  
 0.933
acsA
acetyl-CoA synthase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.933
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
 
 0.919
DR_A0126
Aldehyde dehydrogenase; Similar to PID:1871596 GB:AL123456 percent identity: 63.42; identified by sequence similarity; putative; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.908
acyP
Acylphosphatase, putative; Similar to GB:AE000782 percent identity: 65.12; identified by sequence similarity; putative.
    
 0.904
dctA
C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
 
 
  
 0.718
DR_0810
Dehydrogenase, putative; Similar to GB:Z21955 PID:288223 percent identity: 51.52; identified by sequence similarity; putative.
  
  
 0.692
DR_A0349
ABC transporter, ATP-binding protein; Similar to SP:P27299 GB:Z11796 PID:42023 GB:U00096 PID:1651441 percent identity: 58.82; identified by sequence similarity; putative.
  
 
 0.541
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 
 0.528
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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