node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carA | carB | GSU1273 | GSU1276 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family. | 0.999 |
carA | pyrB | GSU1273 | GSU1271 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | GSU1273 | GSU1272 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.998 |
carA | pyrD | GSU1273 | GSU1755 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.968 |
carA | pyrE | GSU1273 | GSU1637 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.961 |
carA | pyrF | GSU1273 | GSU1461 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.960 |
carA | pyrR | GSU1273 | GSU1270 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Pyrimidine operon regulator and uracil phosphoribosyltransferase PyrR; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.919 |
carA | upp | GSU1273 | GSU0933 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.622 |
carB | carA | GSU1276 | GSU1273 | Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family. | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
carB | pyrB | GSU1276 | GSU1271 | Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family. | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carB | pyrC | GSU1276 | GSU1272 | Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.998 |
carB | pyrD | GSU1276 | GSU1755 | Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.972 |
carB | pyrE | GSU1276 | GSU1637 | Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.966 |
carB | pyrF | GSU1276 | GSU1461 | Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.967 |
carB | pyrH | GSU1276 | GSU1919 | Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.453 |
carB | pyrR | GSU1276 | GSU1270 | Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family. | Pyrimidine operon regulator and uracil phosphoribosyltransferase PyrR; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.926 |
carB | upp | GSU1276 | GSU0933 | Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.524 |
pyrB | carA | GSU1271 | GSU1273 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
pyrB | carB | GSU1271 | GSU1276 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family. | 0.999 |
pyrB | pyrC | GSU1271 | GSU1272 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |