node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GSU1017 | apt | GSU1017 | GSU1526 | Hypoxanthine/guanine phosphoribosyltransferase, putative. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.938 |
GSU1017 | gmk | GSU1017 | GSU2238 | Hypoxanthine/guanine phosphoribosyltransferase, putative. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.924 |
GSU1017 | guaA | GSU1017 | GSU2194 | Hypoxanthine/guanine phosphoribosyltransferase, putative. | Guanosine-5'-monophosphate synthase; Catalyzes the synthesis of GMP from XMP. | 0.953 |
GSU1017 | surE | GSU1017 | GSU1523 | Hypoxanthine/guanine phosphoribosyltransferase, putative. | Nucleoside 3'/5'-monophosphate phosphatase and short-chain exopolyphosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.904 |
apt | GSU1017 | GSU1526 | GSU1017 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine/guanine phosphoribosyltransferase, putative. | 0.938 |
apt | gmk | GSU1526 | GSU2238 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.970 |
apt | guaA | GSU1526 | GSU2194 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanosine-5'-monophosphate synthase; Catalyzes the synthesis of GMP from XMP. | 0.996 |
apt | surE | GSU1526 | GSU1523 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Nucleoside 3'/5'-monophosphate phosphatase and short-chain exopolyphosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.959 |
gmk | GSU1017 | GSU2238 | GSU1017 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypoxanthine/guanine phosphoribosyltransferase, putative. | 0.924 |
gmk | apt | GSU2238 | GSU1526 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.970 |
gmk | guaA | GSU2238 | GSU2194 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanosine-5'-monophosphate synthase; Catalyzes the synthesis of GMP from XMP. | 0.970 |
gmk | ndk | GSU2238 | GSU1110 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.934 |
gmk | nrdJ | GSU2238 | GSU1871 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.910 |
gmk | pyk | GSU2238 | GSU3331 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.924 |
gmk | relA | GSU2238 | GSU2236 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GTP/GDP 3'-pyrophosphokinase and (p)ppGpp 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.962 |
gmk | rpoZ | GSU2238 | GSU2237 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.985 |
gmk | surE | GSU2238 | GSU1523 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside 3'/5'-monophosphate phosphatase and short-chain exopolyphosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.901 |
gmk | yicC | GSU2238 | GSU2239 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Stationary phase survival protein, YicC family, YicC_N and DUF1732 domain-containing; Domains: YicC_N, DUF1732. | 0.916 |
guaA | GSU1017 | GSU2194 | GSU1017 | Guanosine-5'-monophosphate synthase; Catalyzes the synthesis of GMP from XMP. | Hypoxanthine/guanine phosphoribosyltransferase, putative. | 0.953 |
guaA | apt | GSU2194 | GSU1526 | Guanosine-5'-monophosphate synthase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.996 |