node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cbiA | cbiX | GSU3006 | GSU3000 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Sirohydrochlorin cobaltochelatase. | 0.710 |
cbiA | cobC | GSU3006 | GSU3007 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobalamin-5'-phosphate phosphatase, putative. | 0.862 |
cbiA | cobS | GSU3006 | GSU3008 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.971 |
cbiA | cobT | GSU3006 | GSU3009 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.990 |
cbiA | cobU | GSU3006 | GSU3010 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide kinase and adenosylcobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.968 |
cbiA | thiC-2 | GSU3006 | GSU3005 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 4-amino-5-hydroxymethyl-2-methylpyrimidine- phosphate synthase; Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by G.sulfurreducens; Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily. | 0.861 |
cbiX | cbiA | GSU3000 | GSU3006 | Sirohydrochlorin cobaltochelatase. | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.710 |
cbiX | cobC | GSU3000 | GSU3007 | Sirohydrochlorin cobaltochelatase. | Adenosylcobalamin-5'-phosphate phosphatase, putative. | 0.531 |
cbiX | cobS | GSU3000 | GSU3008 | Sirohydrochlorin cobaltochelatase. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.554 |
cbiX | cobT | GSU3000 | GSU3009 | Sirohydrochlorin cobaltochelatase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.533 |
cbiX | cobU | GSU3000 | GSU3010 | Sirohydrochlorin cobaltochelatase. | Adenosylcobinamide kinase and adenosylcobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.791 |
cbiX | thiC-2 | GSU3000 | GSU3005 | Sirohydrochlorin cobaltochelatase. | 4-amino-5-hydroxymethyl-2-methylpyrimidine- phosphate synthase; Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by G.sulfurreducens; Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily. | 0.791 |
cobC | cbiA | GSU3007 | GSU3006 | Adenosylcobalamin-5'-phosphate phosphatase, putative. | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.862 |
cobC | cbiX | GSU3007 | GSU3000 | Adenosylcobalamin-5'-phosphate phosphatase, putative. | Sirohydrochlorin cobaltochelatase. | 0.531 |
cobC | cobS | GSU3007 | GSU3008 | Adenosylcobalamin-5'-phosphate phosphatase, putative. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.985 |
cobC | cobT | GSU3007 | GSU3009 | Adenosylcobalamin-5'-phosphate phosphatase, putative. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.984 |
cobC | cobU | GSU3007 | GSU3010 | Adenosylcobalamin-5'-phosphate phosphatase, putative. | Adenosylcobinamide kinase and adenosylcobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.853 |
cobC | thiC-2 | GSU3007 | GSU3005 | Adenosylcobalamin-5'-phosphate phosphatase, putative. | 4-amino-5-hydroxymethyl-2-methylpyrimidine- phosphate synthase; Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by G.sulfurreducens; Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily. | 0.878 |
cobS | cbiA | GSU3008 | GSU3006 | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.971 |
cobS | cbiX | GSU3008 | GSU3000 | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Sirohydrochlorin cobaltochelatase. | 0.554 |