STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1361Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 41.18; identified by sequence similarity; putative. (292 aa)    
Predicted Functional Partners:
MJ_1450
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 37.27; identified by sequence similarity; putative.
  
     0.569
MJ_1360
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1360.
       0.552
cofE
Conserved hypothetical protein; Catalyzes the GTP-dependent successive addition of two L- glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy- 5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates. Cannot use F420-2 as substrate to add more glutamates. Exhibits maximum activity with GTP, compared with UTP (66%) and dGTP (25%); with ATP, only F420-1 is observed as the product; CTP and TTP support no activity. Belongs to the CofE family.
  
     0.548
aglB
Putative transmembrane oligosaccharyl transferase; Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (ManNAcGlc-2,3-diNAcAGlcNAc in Methanococci) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. Involved in the assembly of an N-linked disaccharide that decorates the S-layer glycoprotein and flagellins.
  
     0.542
MJ_0138
Cobyric acid synthase (cbiP); Similar to GB:M62866 SP:P29932 PID:151151 percent identity: 33.62; identified by sequence similarity; putative.
  
    0.527
mtrH
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit H (mtrH); Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
  
     0.506
MJ_1207
Protease synthase and sporulation negative regulator Pai1, putative; Similar to GB:M36471 SP:P21340 PID:143284 GB:AL009126 percent identity: 35.63; identified by sequence similarity; putative; Belongs to the acetyltransferase family.
  
    0.467
MJ_1359
Conserved hypothetical protein; Similar to GP:1653852 percent identity: 35.56; identified by sequence similarity; putative; Belongs to the UPF0273 family.
       0.446
MJ_0119
Carbon monoxide dehydrogenase gamma subunit (cdhE) isolog; Similar to PID:1002692 SP:Q50539 percent identity: 42.86; identified by sequence similarity; putative.
 
     0.439
MJ_1662
Methyl coenzyme M reductase system, component A2-like; Similar to GB:L11748 PID:293151 PID:385924 GB:AE000666 percent identity: 37.07; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
  
     0.436
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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