node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MG_007 | MG_009 | MG_007 | MG_009 | DNA polymerase III delta prime subunit, putative; Identified by similarity to EGAD:56824. | Deoxyribonuclease, TatD family, putative; Identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010. | 0.861 |
MG_007 | gyrA | MG_007 | MG_004 | DNA polymerase III delta prime subunit, putative; Identified by similarity to EGAD:56824. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.782 |
MG_007 | mnmE | MG_007 | MG_008 | DNA polymerase III delta prime subunit, putative; Identified by similarity to EGAD:56824. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.823 |
MG_007 | serS | MG_007 | MG_005 | DNA polymerase III delta prime subunit, putative; Identified by similarity to EGAD:56824. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.798 |
MG_007 | tmk | MG_007 | MG_006 | DNA polymerase III delta prime subunit, putative; Identified by similarity to EGAD:56824. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.932 |
MG_009 | MG_007 | MG_009 | MG_007 | Deoxyribonuclease, TatD family, putative; Identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010. | DNA polymerase III delta prime subunit, putative; Identified by similarity to EGAD:56824. | 0.861 |
MG_009 | gyrA | MG_009 | MG_004 | Deoxyribonuclease, TatD family, putative; Identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.783 |
MG_009 | mnmE | MG_009 | MG_008 | Deoxyribonuclease, TatD family, putative; Identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.850 |
MG_009 | serS | MG_009 | MG_005 | Deoxyribonuclease, TatD family, putative; Identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.821 |
MG_009 | tmk | MG_009 | MG_006 | Deoxyribonuclease, TatD family, putative; Identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.846 |
gmk | nrdE | MG_107 | MG_231 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase, alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.933 |
gmk | nrdF | MG_107 | MG_229 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase, beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.925 |
gmk | serS | MG_107 | MG_005 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.450 |
gmk | tdk | MG_107 | MG_034 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Thymidine kinase; Identified by similarity to SP:Q03221; match to protein family HMM PF00265. | 0.432 |
gmk | tmk | MG_107 | MG_006 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.873 |
gyrA | MG_007 | MG_004 | MG_007 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA polymerase III delta prime subunit, putative; Identified by similarity to EGAD:56824. | 0.782 |
gyrA | MG_009 | MG_004 | MG_009 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Deoxyribonuclease, TatD family, putative; Identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010. | 0.783 |
gyrA | mnmE | MG_004 | MG_008 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.783 |
gyrA | serS | MG_004 | MG_005 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.861 |
gyrA | tmk | MG_004 | MG_006 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.782 |