node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MG_010 | dnaB | MG_010 | MG_094 | DNA primase-related protein; Identified by similarity to EGAD:56796; match to protein family HMM PF01751; match to protein family HMM TIGR00646. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | 0.893 |
MG_010 | dnaG | MG_010 | MG_250 | DNA primase-related protein; Identified by similarity to EGAD:56796; match to protein family HMM PF01751; match to protein family HMM TIGR00646. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.907 |
MG_095 | dnaB | MG_095 | MG_094 | Lipoprotein, putative; Identified by similarity to EGAD:57278. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | 0.787 |
MG_095 | rplI | MG_095 | MG_093 | Lipoprotein, putative; Identified by similarity to EGAD:57278. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.774 |
MG_095 | rpsF | MG_095 | MG_090 | Lipoprotein, putative; Identified by similarity to EGAD:57278. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.774 |
MG_095 | rpsR | MG_095 | MG_092 | Lipoprotein, putative; Identified by similarity to EGAD:57278. | Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.774 |
MG_095 | ssb | MG_095 | MG_091 | Lipoprotein, putative; Identified by similarity to EGAD:57278. | Identified by similarity to EGAD:11594; match to protein family HMM PF00436. | 0.774 |
dnaA | dnaB | MG_469 | MG_094 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity). | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | 0.909 |
dnaA | dnaX | MG_469 | MG_419 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity). | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity; Belongs to the DnaX/STICHEL family. | 0.504 |
dnaA | ssb | MG_469 | MG_091 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity). | Identified by similarity to EGAD:11594; match to protein family HMM PF00436. | 0.403 |
dnaB | MG_010 | MG_094 | MG_010 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | DNA primase-related protein; Identified by similarity to EGAD:56796; match to protein family HMM PF01751; match to protein family HMM TIGR00646. | 0.893 |
dnaB | MG_095 | MG_094 | MG_095 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | Lipoprotein, putative; Identified by similarity to EGAD:57278. | 0.787 |
dnaB | dnaA | MG_094 | MG_469 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity). | 0.909 |
dnaB | dnaG | MG_094 | MG_250 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.976 |
dnaB | dnaX | MG_094 | MG_419 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity; Belongs to the DnaX/STICHEL family. | 0.821 |
dnaB | rplI | MG_094 | MG_093 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.867 |
dnaB | rpsF | MG_094 | MG_090 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.803 |
dnaB | rpsR | MG_094 | MG_092 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.849 |
dnaB | ssb | MG_094 | MG_091 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | Identified by similarity to EGAD:11594; match to protein family HMM PF00436. | 0.922 |
dnaB | uvrD | MG_094 | MG_244 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | UvrD/REP helicase; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair (By similarity); Belongs to the helicase family. UvrD subfamily. | 0.818 |