STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_109Serine/threonine protein kinase, putative; MG109 has 1 transmembrane region; identified by similarity to GB:AAL58474.1; match to protein family HMM PF00069; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (387 aa)    
Predicted Functional Partners:
MG_108
Protein phosphatase 2C, putative; Identified by similarity to EGAD:57254; match to protein family HMM PF00481.
 
 
 0.996
hmw3
HMW3 cytadherence accessory protein; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle. Essential for successful surface parasitism (By similarity).
   
 
 0.952
rsgA
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
  
 0.860
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
       0.841
rpe
Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
  
  
 0.821
MG_207
Identified by similarity to EGAD:57314; match to protein family HMM PF00149; match to protein family HMM TIGR00040; Belongs to the metallophosphoesterase superfamily. YfcE family.
     
 0.787
MG_246
Identified by similarity to PDB:1T71_A; match to protein family HMM PF00149; match to protein family HMM TIGR00282.
      
 0.750
pgi
Glucose-6-phosphate isomerase; MG111 has 1 transmembrane region; identified by similarity to SP:P81181; match to protein family HMM PF00342.
       0.748
asnS
asparaginyl-tRNA synthetase; Identified by similarity to EGAD:57244; match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457.
       0.718
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.711
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
Server load: low (26%) [HD]