node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MG_018 | polA | MG_018 | MG_262 | Helicase SNF2 family, putative; Identified by similarity to EGAD:56776; match to protein family HMM PF00176; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04434. | 5'-3' exonuclease, putative; 5'-3' exonuclease acting preferentially on double-stranded DNA. | 0.966 |
MG_018 | recA | MG_018 | MG_339 | Helicase SNF2 family, putative; Identified by similarity to EGAD:56776; match to protein family HMM PF00176; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04434. | recA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.934 |
MG_018 | rpoA | MG_018 | MG_177 | Helicase SNF2 family, putative; Identified by similarity to EGAD:56776; match to protein family HMM PF00176; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04434. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.995 |
MG_018 | rpoC | MG_018 | MG_340 | Helicase SNF2 family, putative; Identified by similarity to EGAD:56776; match to protein family HMM PF00176; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04434. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.967 |
MG_018 | topA | MG_018 | MG_122 | Helicase SNF2 family, putative; Identified by similarity to EGAD:56776; match to protein family HMM PF00176; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04434. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.843 |
MG_018 | uvrD | MG_018 | MG_244 | Helicase SNF2 family, putative; Identified by similarity to EGAD:56776; match to protein family HMM PF00176; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04434. | UvrD/REP helicase; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair (By similarity); Belongs to the helicase family. UvrD subfamily. | 0.843 |
asnS | leuS | MG_113 | MG_266 | asparaginyl-tRNA synthetase; Identified by similarity to EGAD:57244; match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | leucyl-tRNA synthetase; Identified by similarity to SP:P36430; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.898 |
asnS | polA | MG_113 | MG_262 | asparaginyl-tRNA synthetase; Identified by similarity to EGAD:57244; match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | 5'-3' exonuclease, putative; 5'-3' exonuclease acting preferentially on double-stranded DNA. | 0.578 |
asnS | recA | MG_113 | MG_339 | asparaginyl-tRNA synthetase; Identified by similarity to EGAD:57244; match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | recA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.453 |
asnS | topA | MG_113 | MG_122 | asparaginyl-tRNA synthetase; Identified by similarity to EGAD:57244; match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.849 |
leuS | asnS | MG_266 | MG_113 | leucyl-tRNA synthetase; Identified by similarity to SP:P36430; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | asparaginyl-tRNA synthetase; Identified by similarity to EGAD:57244; match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | 0.898 |
leuS | ligA | MG_266 | MG_254 | leucyl-tRNA synthetase; Identified by similarity to SP:P36430; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.826 |
leuS | polA | MG_266 | MG_262 | leucyl-tRNA synthetase; Identified by similarity to SP:P36430; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | 5'-3' exonuclease, putative; 5'-3' exonuclease acting preferentially on double-stranded DNA. | 0.406 |
leuS | recA | MG_266 | MG_339 | leucyl-tRNA synthetase; Identified by similarity to SP:P36430; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | recA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.554 |
leuS | rpoA | MG_266 | MG_177 | leucyl-tRNA synthetase; Identified by similarity to SP:P36430; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.636 |
leuS | rpoC | MG_266 | MG_340 | leucyl-tRNA synthetase; Identified by similarity to SP:P36430; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.473 |
leuS | topA | MG_266 | MG_122 | leucyl-tRNA synthetase; Identified by similarity to SP:P36430; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.999 |
ligA | leuS | MG_254 | MG_266 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | leucyl-tRNA synthetase; Identified by similarity to SP:P36430; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.826 |
ligA | polA | MG_254 | MG_262 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 5'-3' exonuclease, putative; 5'-3' exonuclease acting preferentially on double-stranded DNA. | 0.684 |
ligA | recA | MG_254 | MG_339 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | recA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.496 |