STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_132HIT domain protein; Identified by similarity to EGAD:57208; match to protein family HMM PF01230. (141 aa)    
Predicted Functional Partners:
MG_133
Membrane protein, putative; MG133 has 5 transmembrane regions; identified by similarity to EGAD:57206.
       0.774
MG_134
Conserved hypothetical protein; Identified by similarity to EGAD:57204; match to protein family HMM PF02575; match to protein family HMM TIGR00103.
       0.629
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.590
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.571
hmw1
HMW1 cytadherence accessory protein; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle (By similarity).
     
 0.569
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.532
MG_308
ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by similarity to EGAD:57201; match to protein family HMM PF00270; match to protein family HMM PF00271.
  
 
  0.420
MG_425
ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by similarity to EGAD:56787; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851.
  
 
  0.420
MG_018
Helicase SNF2 family, putative; Identified by similarity to EGAD:56776; match to protein family HMM PF00176; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04434.
   
 
  0.418
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
 
 0.403
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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