STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_140Conserved hypothetical protein; Identified by similarity to EGAD:57280; Belongs to the DNA2/NAM7 helicase family. (1113 aa)    
Predicted Functional Partners:
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
       0.782
MG_146
Conserved hypothetical protein; MG146 has 4 transmembrane regioins and a CBS domain pair; identified by similarity to EGAD:57267; match to protein family HMM PF00571; match to protein family HMM PF01595.
 
     0.776
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
       0.774
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
       0.773
MG_477
Conserved hypothetical protein; old_locus_tag=MG141.1; identified by similarity to GP:14247037; match to protein family HMM PF04296.
       0.773
ribF
Riboflavin biosynthesis protein RibF; Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
       0.694
MG_144
Conserved hypothetical protein; MG144 has 3 transmembrane regions; identified by similarity to EGAD:57271.
       0.693
MG_260
Lipoprotein, putative; Identified by similarity to EGAD:57182; match to protein family HMM PF03202; match to protein family HMM PF03305.
 
   
 0.687
MG_185
Lipoprotein, putative; Identified by similarity to EGAD:36928; match to protein family HMM PF03202; match to protein family HMM PF03305.
 
     0.685
MG_147
Membrane protein, putative; MG147 has 7 transmembrane regions; identified by similarity to EGAD:57265.
       0.670
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.