STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_146Conserved hypothetical protein; MG146 has 4 transmembrane regioins and a CBS domain pair; identified by similarity to EGAD:57267; match to protein family HMM PF00571; match to protein family HMM PF01595. (424 aa)    
Predicted Functional Partners:
MG_140
Conserved hypothetical protein; Identified by similarity to EGAD:57280; Belongs to the DNA2/NAM7 helicase family.
 
     0.776
MG_147
Membrane protein, putative; MG147 has 7 transmembrane regions; identified by similarity to EGAD:57265.
       0.774
ribF
Riboflavin biosynthesis protein RibF; Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
       0.751
MG_144
Conserved hypothetical protein; MG144 has 3 transmembrane regions; identified by similarity to EGAD:57271.
       0.746
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
       0.700
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
       0.695
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
    0.692
MG_477
Conserved hypothetical protein; old_locus_tag=MG141.1; identified by similarity to GP:14247037; match to protein family HMM PF04296.
       0.685
MG_148
Conserved hypothetical protein; Identified by similarity to EGAD:57263.
       0.646
MG_149
Lipoprotein, putative; Identified by similarity to EGAD:57261.
       0.476
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.