STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lspASignal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (181 aa)    
Predicted Functional Partners:
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
   
 0.885
MG_209
Pseudouridine synthase, RluA family; Identified by similarity to EGAD:57156; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005.
  
    0.855
MG_208
Glycoprotease family protein; The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)); identified by similarity to EGAD:57160; match to protein family HMM PF00814.
 
     0.849
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
  
 0.797
MG_316
ComEC/Rec2-related protein; MG316 has 9 transmembrane regions; identified by similarity to EGAD:36295; match to protein family HMM PF03772; match to protein family HMM TIGR00360.
 
   
 0.795
MG_064
ABC transporter, permease protein, putative; MG064 and MG065 comprise a likely ABC transporter cassette. There is no likely substrate binding protein in the genome vicinity. MG064 has 8 transmembrane regions; identified by similarity to EGAD:56854; match to protein family HMM PF02687.
 
  
 0.781
scpA
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity).
 
  
 0.763
MG_040
Lipoprotein, putative; Identified by similarity to EGAD:57299; match to protein family HMM PF02608.
 
   
 0.751
MG_133
Membrane protein, putative; MG133 has 5 transmembrane regions; identified by similarity to EGAD:57206.
      
 0.750
scpB
Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
  
  
 0.690
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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