STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (309 aa)    
Predicted Functional Partners:
mraZ
mraZ protein; Identified by similarity to EGAD:57052; match to protein family HMM PF02381; match to protein family HMM TIGR00242.
  
  
 0.993
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 0.985
MG_223
Conserved hypothetical protein; Identified by similarity to EGAD:57046.
  
  
 0.931
rpsI
Ribosomal protein S9; Identified by similarity to SP:P21470; match to protein family HMM PF00380; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.833
rpsP
Ribosomal protein S16; Identified by similarity to SP:P21474; match to protein family HMM PF00886; match to protein family HMM TIGR00002.
  
   0.790
rpsO
Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
 
 0.788
rsmI
Tetrapyrrole (corrin/porphyrin) methylase protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
     
 0.787
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
    
 
 0.775
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.735
rpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
  
 
 0.723
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.