node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MG_037 | MG_115 | MG_037 | MG_115 | Nicotinate phosphoribosyltransferase (NAPRTase) family; Identified by similarity to GB:AAP96260.1; match to protein family HMM PF04095; Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA domain protein; Identified by similarity to EGAD:31034; match to protein family HMM PF02464; match to protein family HMM TIGR00199; Belongs to the CinA family. | 0.920 |
MG_037 | MG_240 | MG_037 | MG_240 | Nicotinate phosphoribosyltransferase (NAPRTase) family; Identified by similarity to GB:AAP96260.1; match to protein family HMM PF04095; Belongs to the NAPRTase family. | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | 0.962 |
MG_037 | glyA | MG_037 | MG_394 | Nicotinate phosphoribosyltransferase (NAPRTase) family; Identified by similarity to GB:AAP96260.1; match to protein family HMM PF04095; Belongs to the NAPRTase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.454 |
MG_037 | nadE | MG_037 | MG_383 | Nicotinate phosphoribosyltransferase (NAPRTase) family; Identified by similarity to GB:AAP96260.1; match to protein family HMM PF04095; Belongs to the NAPRTase family. | NH(3)-dependent NAD+ synthetase, putative; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.556 |
MG_037 | nadK | MG_037 | MG_128 | Nicotinate phosphoribosyltransferase (NAPRTase) family; Identified by similarity to GB:AAP96260.1; match to protein family HMM PF04095; Belongs to the NAPRTase family. | Inorganic polyphosphate/ATP-NAD kinase, probable; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.450 |
MG_115 | MG_037 | MG_115 | MG_037 | Competence/damage-inducible protein CinA domain protein; Identified by similarity to EGAD:31034; match to protein family HMM PF02464; match to protein family HMM TIGR00199; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase (NAPRTase) family; Identified by similarity to GB:AAP96260.1; match to protein family HMM PF04095; Belongs to the NAPRTase family. | 0.920 |
MG_115 | MG_240 | MG_115 | MG_240 | Competence/damage-inducible protein CinA domain protein; Identified by similarity to EGAD:31034; match to protein family HMM PF02464; match to protein family HMM TIGR00199; Belongs to the CinA family. | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | 0.959 |
MG_115 | nadE | MG_115 | MG_383 | Competence/damage-inducible protein CinA domain protein; Identified by similarity to EGAD:31034; match to protein family HMM PF02464; match to protein family HMM TIGR00199; Belongs to the CinA family. | NH(3)-dependent NAD+ synthetase, putative; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.449 |
MG_240 | MG_037 | MG_240 | MG_037 | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | Nicotinate phosphoribosyltransferase (NAPRTase) family; Identified by similarity to GB:AAP96260.1; match to protein family HMM PF04095; Belongs to the NAPRTase family. | 0.962 |
MG_240 | MG_115 | MG_240 | MG_115 | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | Competence/damage-inducible protein CinA domain protein; Identified by similarity to EGAD:31034; match to protein family HMM PF02464; match to protein family HMM TIGR00199; Belongs to the CinA family. | 0.959 |
MG_240 | coaE | MG_240 | MG_264 | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.668 |
MG_240 | ftsH | MG_240 | MG_457 | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.666 |
MG_240 | glyA | MG_240 | MG_394 | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.670 |
MG_240 | nadE | MG_240 | MG_383 | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | NH(3)-dependent NAD+ synthetase, putative; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.967 |
MG_240 | nadK | MG_240 | MG_128 | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | Inorganic polyphosphate/ATP-NAD kinase, probable; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.961 |
MG_240 | obg | MG_240 | MG_384 | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | GTPase1 Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.599 |
MG_240 | rbgA | MG_240 | MG_442 | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | GTP-binding conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. Binds to the 23S rRNA (By similarity). Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.635 |
MG_240 | tpiA | MG_240 | MG_431 | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.629 |
coaE | MG_240 | MG_264 | MG_240 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488. | 0.668 |
coaE | nadE | MG_264 | MG_383 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | NH(3)-dependent NAD+ synthetase, putative; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.476 |