STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa)    
Predicted Functional Partners:
acpS
Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
    
  0.903
ribF
Riboflavin biosynthesis protein RibF; Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
 
  
 0.830
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
  
  
 0.818
MG_263
Cof-like hydrolase; Identified by similarity to EGAD:57126; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484.
       0.774
MG_356
Choline/ethanolamine kinase, putative; Identified by similarity to EGAD:56833; match to protein family HMM PF01633; match to protein family HMM PF01636.
     
 0.751
MG_268
Conserved hypothetical protein; MG268 is similar to deoxynucleoside kinase; however it is not similar enough to warrent such an annotation. This gene is not essential (Glass et al 1005 and Hutchison et al, 1999); identified by similarity to EGAD:57101.
      
 0.750
pyk
Pyruvate kinase; Identified by similarity to SP:Q02499; match to protein family HMM PF00224; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
     
 0.721
polA
5'-3' exonuclease, putative; 5'-3' exonuclease acting preferentially on double-stranded DNA.
  
  
 0.712
nadK
Inorganic polyphosphate/ATP-NAD kinase, probable; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.687
MG_240
Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; match to protein family HMM TIGR00488.
     
 0.668
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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