node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fba | ldh | MG_023 | MG_460 | Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | 0.937 |
fba | pdhA | MG_023 | MG_274 | Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Pyruvate dehydrogenase component E1, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.848 |
fba | pdhB | MG_023 | MG_273 | Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Pyruvate dehydrogenase component E1, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.909 |
fba | pgi | MG_023 | MG_111 | Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Glucose-6-phosphate isomerase; MG111 has 1 transmembrane region; identified by similarity to SP:P81181; match to protein family HMM PF00342. | 0.979 |
fba | pyk | MG_023 | MG_216 | Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Pyruvate kinase; Identified by similarity to SP:Q02499; match to protein family HMM PF00224; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.925 |
fba | tkt | MG_023 | MG_066 | Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.963 |
ldh | fba | MG_460 | MG_023 | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 0.937 |
ldh | lpdA | MG_460 | MG_271 | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.599 |
ldh | nox | MG_460 | MG_275 | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | NADH oxidase; Catalyzes the four-electron reduction of molecular oxygen to water; Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family. | 0.527 |
ldh | pdhA | MG_460 | MG_274 | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | Pyruvate dehydrogenase component E1, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.956 |
ldh | pdhB | MG_460 | MG_273 | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | Pyruvate dehydrogenase component E1, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.964 |
ldh | pdhC | MG_460 | MG_272 | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.679 |
ldh | pgi | MG_460 | MG_111 | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | Glucose-6-phosphate isomerase; MG111 has 1 transmembrane region; identified by similarity to SP:P81181; match to protein family HMM PF00342. | 0.962 |
ldh | pyk | MG_460 | MG_216 | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | Pyruvate kinase; Identified by similarity to SP:Q02499; match to protein family HMM PF00224; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.977 |
ldh | tkt | MG_460 | MG_066 | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.899 |
lpdA | ldh | MG_271 | MG_460 | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | 0.599 |
lpdA | lplA | MG_271 | MG_270 | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Lipoyltransferase/lipoate-protein ligase, putative; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes; Belongs to the LplA family. | 0.987 |
lpdA | nox | MG_271 | MG_275 | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | NADH oxidase; Catalyzes the four-electron reduction of molecular oxygen to water; Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family. | 0.905 |
lpdA | pdhA | MG_271 | MG_274 | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Pyruvate dehydrogenase component E1, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.998 |
lpdA | pdhB | MG_271 | MG_273 | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Pyruvate dehydrogenase component E1, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.999 |