STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_323Potassium uptake protein, TrkA family; MG322, the adjacent gene, which is on the opposite strand encodes a trk potassium uptake protein. MG323 is a likely accessory protein; identified by similarity to EGAD:57150; match to protein family HMM PF02080; match to protein family HMM PF02254. (227 aa)    
Predicted Functional Partners:
MG_322
Potassium uptake protein, TrkH family, putative; The adjacent gene, MG323, is a likely TrkA accessory protein for this gene which has some similarity to TrkH potassium transporters. MG322 has 9 transmembrane regions; identified by similarity to EGAD:57154; match to protein family HMM PF02386.
 
 
 0.999
pacL
ATPase, P-type (transporting), HAD superfamily, subfamily IC; Could mediate calcium influx.
  
  
 0.832
MG_245
5-formyltetrahydrofolate cyclo-ligase, putative; Involved in folate metabolism. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10- methenyltetrahydrofolate (By similarity).
  
 
 0.803
MG_208
Glycoprotease family protein; The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)); identified by similarity to EGAD:57160; match to protein family HMM PF00814.
   
 
 0.786
pepP
Metallopeptidase family M24 aminopeptidase; Identified by similarity to GB:AAN81374.1; match to protein family HMM PF00557; Belongs to the peptidase M24B family.
     
 0.710
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity).
     
 0.682
pstA
Phosphate ABC transporter, permease protein PstA; Could be part of a binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
  
  
 0.670
pepF
Identified by similarity to SP:Q53778; match to protein family HMM PF01432; match to protein family HMM TIGR00181.
     
 0.667
pip
Proline iminopeptidase; Specifically catalyzes the removal of N-terminal proline residues from peptides.
     
 0.660
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
     
 0.659
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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