STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepPMetallopeptidase family M24 aminopeptidase; Identified by similarity to GB:AAN81374.1; match to protein family HMM PF00557; Belongs to the peptidase M24B family. (354 aa)    
Predicted Functional Partners:
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity).
  
 
 0.896
pepF
Identified by similarity to SP:Q53778; match to protein family HMM PF01432; match to protein family HMM TIGR00181.
     
 0.873
rpmG
Ribosomal protein L33; Identified by similarity to EGAD:57100; match to protein family HMM PF00471; match to protein family HMM TIGR01023; Belongs to the bacterial ribosomal protein bL33 family.
       0.839
MG_515
Conserved hypothetical protein; MG323.1 has 4 transmembrane proteins. old_locus_tag=MG323.1; identified by similarity to EGAD:57110.
  
    0.785
MG_327
Hydrolase, alpha/beta fold family; MG327 belongs to the SwissProt lipase/esterase LIP3/bchO family; however the similarity to characterized lipase/esterases is weak, even with the Mycoplasma mycoides triplet of lipase/esterases (PMID: 7789792); identified by similarity to EGAD:57089; match to protein family HMM PF00561.
   
 
 0.747
MG_245
5-formyltetrahydrofolate cyclo-ligase, putative; Involved in folate metabolism. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10- methenyltetrahydrofolate (By similarity).
     
 0.744
MG_326
degV family protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
       0.744
pacL
ATPase, P-type (transporting), HAD superfamily, subfamily IC; Could mediate calcium influx.
  
 
 0.740
folD
Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.724
MG_328
Conserved hypothetical protein; MG328 has 5 M protein repeats. These short repeats are found in multiple copies in bacterial M proteins. The M proteins bind to IgA and are closely associated with virulence; identified by similarity to EGAD:57085.
       0.722
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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