STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_381Conserved hypothetical protein; Identified by similarity to EGAD:57069. (218 aa)    
Predicted Functional Partners:
gidA
Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
       0.774
rsmG
Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
       0.774
argS
arginyl-tRNA synthetase; Identified by similarity to SP:P46906; match to protein family HMM PF00750; match to protein family HMM PF05746; match to protein family HMM TIGR00456.
       0.566
MG_370
Pseudouridine synthase, RluA family; MG370 is not essential for growth on SP-4 media (Hutchison, et al., 1999; Glass, et al., 2005); identified by similarity to EGAD:57124; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005.
       0.468
MG_371
DHH family protein; Identified by similarity to EGAD:57119; match to protein family HMM PF01368; match to protein family HMM PF02272; Belongs to the mgp1/MG371 family.
       0.468
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.468
MG_373
Conserved hypothetical protein; Identified by similarity to EGAD:57109.
       0.468
MG_374
Conserved hypothetical protein; Identified by similarity to EGAD:57104.
       0.468
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
       0.468
MG_376
Conserved hypothetical protein; Identified by similarity to EGAD:57091.
       0.468
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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