STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_389Conserved hypothetical protein; MG389 has 1 transmembrane region; identified by similarity to EGAD:57010. (127 aa)    
Predicted Functional Partners:
MG_390
ABC transporter, ATP-binding/permease protein; MG390 has 4 transmembrane regions, plus and ATP binding domain, and a peptidase domain. There is no predicted substrate binding protein or other ABC transporter component in the vicinity; identified by similarity to GB:AAA03343.1; match to protein family HMM PF00005; match to protein family HMM PF03412.
     
 0.922
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
       0.773
ybeY
Expressed protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA; Belongs to the endoribonuclease YbeY family.
       0.773
MG_220
Conserved hypothetical protein; MG220 has 1 transmembrane region; identified by similarity to EGAD:57057.
   
  
 0.769
MG_281
Conserved hypothetical protein; MG281 has 1 transmembrane region; identified by similarity to EGAD:57033.
      
 0.685
MG_428
MG428, which has features of a LuxR bacterial regulatory protein, is not essential for growth in SP-4 (Glass, et al., 2005); identified by similarity to EGAD:56778.
      
 0.550
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity).
       0.518
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family.
       0.496
groES
Chaperonin, 10 kDa (GroES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
       0.487
MG_385
Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. MG293 and MG385 comprise a parrologous gene family. Both can be disrupted when grown on SP-4 media(Glass et al. 2005); identified by similarity to SP:P37965; match to protein family HMM PF03009.
       0.410
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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