STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_390ABC transporter, ATP-binding/permease protein; MG390 has 4 transmembrane regions, plus and ATP binding domain, and a peptidase domain. There is no predicted substrate binding protein or other ABC transporter component in the vicinity; identified by similarity to GB:AAA03343.1; match to protein family HMM PF00005; match to protein family HMM PF03412. (660 aa)    
Predicted Functional Partners:
MG_389
Conserved hypothetical protein; MG389 has 1 transmembrane region; identified by similarity to EGAD:57010.
     
 0.922
MG_014
ABC transporter, ATP-binding/permease protein; MG014 has 6 transmembrane regions plus an ATP binding domain; identified by similarity to EGAD:56782; match to protein family HMM PF00005; match to protein family HMM PF00664.
   
   0.871
MG_015
ABC transporter, ATP-binding/permease protein; MG015 has 5 transmembrane regions plus an ATP binding domain; identified by similarity to EGAD:56779; match to protein family HMM PF00005; match to protein family HMM PF00664.
   
   0.871
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
       0.841
MG_395
Lipoprotein, putative; Identified by similarity to EGAD:41340; match to protein family HMM PF01727; match to protein family HMM PF01732.
     
 0.826
ybeY
Expressed protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA; Belongs to the endoribonuclease YbeY family.
       0.803
MG_397
Conserved hypothetical protein; MG397 has 1 transmembrane region; identified by similarity to EGAD:35551.
     
 0.795
p200
P200 protein; Could be an accessory structural component in cytadherence.
 
     0.784
hmw2
HMW2 cytadherence accessory protein; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle (By similarity).
 
   
 0.753
MG_468
ABC transporter, permease protein; MG468 has 8 transmembrane regions. The gene is part of a likely ABC transporter cassette. The flanking genes are both ATPases. There is no evidence of a substrante binding protein; identified by similarity to EGAD:36850; match to protein family HMM PF02687.
 
    0.752
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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