STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MG_459Conserved hypothetical protein; MG459 may encode a 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; however M. genitalium does not synthesize isoprenyl pyrophosphate via deoxyxylulose; identified by similarity to EGAD:56901; match to protein family HMM PF02542. (169 aa)    
Predicted Functional Partners:
hpt
Hypoxanthine phosphoribosyltransferase; Identified by similarity to SP:Q02522; match to protein family HMM PF00156; match to protein family HMM TIGR01203.
     
 0.792
MG_116
Conserved hypothetical protein; Identified by similarity to EGAD:57240.
  
  
 0.765
ldh
L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
       0.528
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.
       0.481
Your Current Organism:
Mycoplasma genitalium
NCBI taxonomy Id: 243273
Other names: M. genitalium G37, Mycoplasma genitalium ATCC 33530, Mycoplasma genitalium G37, Mycoplasma genitalium str. G37, Mycoplasma genitalium strain G37
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.