STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TDE_0630Sigma factor regulatory protein, putative; Identified by similarity to SP:P40399. (483 aa)    
Predicted Functional Partners:
TDE_0632
Anti-anti-sigma factor; Identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.955
TDE_1122
Anti-anti-sigma factor; Identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.924
TDE_2083
Anti-anti-sigma factor; Identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.895
TDE_0631
Sigma factor regulatory protein, putative; Identified by similarity to SP:P40399.
 
    
0.845
TDE_0102
Cyclic nucleotide-binding protein; Identified by match to protein family HMM PF00027.
  
 
 0.763
TDE_1008
Flagellar protein, putative; Identified by similarity to SP:P57427.
   
    0.756
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
     
 0.753
TDE_1121
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.732
TDE_0128
HAMP domain/GGDEF domain/EAL domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00672; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
  
  
 0.714
TDE_2075
GGDEF domain/EAL domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254; match to protein family HMM TIGR01612.
  
  
 0.714
Your Current Organism:
Treponema denticola
NCBI taxonomy Id: 243275
Other names: T. denticola ATCC 35405, Treponema denticola ATCC 35405, Treponema denticola str. ATCC 35405
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