STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TDE_2619RNA methyltransferase, TrmA family, putative; Identified by match to protein family HMM PF01938; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (404 aa)    
Predicted Functional Partners:
cmk-2
Cytidylate kinase/ribosomal protein S1; Identified by match to protein family HMM PF00575; match to protein family HMM PF02224; match to protein family HMM TIGR00017; match to protein family HMM TIGR00717.
  
    0.806
TDE_2618
PHP domain protein; Identified by similarity to OMNI:NTL01NM00595; match to protein family HMM PF02231.
       0.782
trmB
Methyltransferase, putative; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.704
TDE_2620
Conserved hypothetical protein; Identified by similarity to GP:19714407.
       0.637
TDE_2162
Identified by match to protein family HMM PF01189; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.613
TDE_2621
Hypothetical protein; Identified by Glimmer2; putative.
       0.606
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.576
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
  
    0.565
maf
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     0.546
TDE_2617
Cyclic nucleotide-binding protein; Identified by match to protein family HMM PF00027; match to protein family HMM PF00515.
       0.540
Your Current Organism:
Treponema denticola
NCBI taxonomy Id: 243275
Other names: T. denticola ATCC 35405, Treponema denticola ATCC 35405, Treponema denticola str. ATCC 35405
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.