STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0854Predicted coding region TP0854; Hypothetical protein; identified by Glimmer; putative. (1533 aa)    
Predicted Functional Partners:
TP_0233
Anti-sigma F factor antagonist, putative; Similar to GB:M25260 SP:P26777 PID:304171 percent identity: 25.26; identified by sequence similarity; putative; Belongs to the anti-sigma-factor antagonist family.
 
 0.979
TP_0540
Anti-sigma F factor antagonist (spoIIAA-2); Similar to GB:M17643 SP:P10727 PID:143613 PID:1303998 GB:AL009126 percent identity: 23.23; identified by sequence similarity; putative; Belongs to the anti-sigma-factor antagonist family.
 
 0.923
TP_0220
Anti-sigma F factor antagonist (spoIIAA-1); Similar to GB:M25260 SP:P26777 PID:304171 percent identity: 29.35; identified by sequence similarity; putative; Belongs to the anti-sigma-factor antagonist family.
  
 0.894
TP_0959
Predicted coding region TP0959; Hypothetical protein; identified by Glimmer; putative.
   
    0.851
TP_0855
Predicted coding region TP0855; Hypothetical protein; identified by Glimmer; putative.
       0.837
TP_0567
Conserved hypothetical protein; Similar to PID:1165270 PID:1196323 GB:AE000783 percent identity: 30.48; identified by sequence similarity; putative.
  
    0.805
fliM
Flagellar motor switch protein (fliM); FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
  
    0.767
flgB
Flagellar basal-body rod protein (flgB); Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.750
fliH
Flagellar assembly protein (fliH); Needed for flagellar regrowth and assembly; Belongs to the FliH family.
 
    0.744
flgK
Flagellar hook-associated protein 1 (flgK); Similar to SP:P70859 PID:1518046 GB:AE000783 percent identity: 39.78; identified by sequence similarity; putative.
  
    0.740
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.