STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comEcomE protein, putative; Similar to PID:1652202 percent identity: 27.72; identified by sequence similarity; putative. (566 aa)    
Predicted Functional Partners:
rsmA
Dimethyladenosine transferase (ksgA); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
     0.856
TP_0338
Predicted coding region TP0338; Hypothetical protein; identified by Glimmer; putative.
       0.741
rluA2
Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.726
dprA
Smf protein (smf); Similar to PID:1165281 PID:1196312 PID:1234878 GB:AE000783 percent identity: 32.71; identified by sequence similarity; putative.
  
  
 0.725
TP_0776
Conserved hypothetical protein; Similar to SP:P46846 PID:606348 GB:U00096 PID:1789818 percent identity: 25.13; identified by sequence similarity; putative.
  
  
 0.690
recA
recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.592
TP_0335
Predicted coding region TP0335; Hypothetical protein; identified by Glimmer; putative.
       0.572
recJ
single-stranded-DNA-specific exonuclease (recJ); Similar to GB:AE000783 percent identity: 24.42; identified by sequence similarity; putative.
     
 0.423
prfA
Peptide chain release factor 1 (prfA); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.413
fliP
Flagellar biosynthetic protein (fliP); Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
   
    0.410
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.