STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comEcomE protein, putative; Similar to PID:1652202 percent identity: 27.72; identified by sequence similarity; putative. (566 aa)    
Predicted Functional Partners:
rsmA
Dimethyladenosine transferase (ksgA); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
     0.870
dprA
Smf protein (smf); Similar to PID:1165281 PID:1196312 PID:1234878 GB:AE000783 percent identity: 32.71; identified by sequence similarity; putative.
  
  
 0.788
TP_0776
Conserved hypothetical protein; Similar to SP:P46846 PID:606348 GB:U00096 PID:1789818 percent identity: 25.13; identified by sequence similarity; putative.
  
  
 0.764
TP_0338
Predicted coding region TP0338; Hypothetical protein; identified by Glimmer; putative.
       0.733
rluA2
Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.726
cmk
Ribosomal protein S1 (rpsA); Similar to SP:P02349 GB:V00342 GB:V00352 GB:X04864 PID:42837 percent identity: 36.77; identified by sequence similarity; putative.
     
 0.669
recA
recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.644
TP_0335
Predicted coding region TP0335; Hypothetical protein; identified by Glimmer; putative.
       0.572
TP_0567
Conserved hypothetical protein; Similar to PID:1165270 PID:1196323 GB:AE000783 percent identity: 30.48; identified by sequence similarity; putative.
   
    0.472
fliP
Flagellar biosynthetic protein (fliP); Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
   
    0.471
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.