STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recBATP-dependent nuclease, subunit A, putative; Similar to GB:M63489 SP:P23478 PID:142440 PID:2145362 PID:2226192 percent identity: 29.14; identified by sequence similarity; putative; Belongs to the helicase family. UvrD subfamily. (1239 aa)    
Predicted Functional Partners:
TP_0899
Predicted coding region TP0899; Hypothetical protein; identified by Glimmer; putative.
  
 
 0.992
TP_0900
Predicted coding region TP0900; Hypothetical protein; identified by Glimmer; putative.
  
 
 0.992
recQ
ATP-dependent DNA helicase, putative; Similar to GB:M87049 SP:P15043 GB:M30198 PID:147559 PID:148221 percent identity: 38.81; identified by sequence similarity; putative.
    
 0.903
TP_0896
Predicted coding region TP0896; Hypothetical protein; identified by Glimmer; putative.
     
 0.828
TP_0897
Tpr protein K (tprK); Similar to GP:2196926 percent identity: 40.87; identified by sequence similarity; putative.
       0.773
recA
recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.727
TP_0894
Conserved hypothetical protein; Similar to PID:1652748 percent identity: 36.70; identified by sequence similarity; putative.
       0.722
TP_0895
Predicted coding region TP0895; Hypothetical protein; identified by Glimmer; putative.
       0.714
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.704
uvrD
DNA helicase II (uvrD); Similar to GP:2618592 percent identity: 40.96; identified by sequence similarity; putative.
 
  
0.704
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.