STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1234Similar to SP:P04995 GB:J02641 GB:U00009 PID:405954 PID:147788; identified by sequence similarity; putative. (474 aa)    
Predicted Functional Partners:
VC_1233
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.833
VC_2417
single-stranded-DNA-specific exonuclease RecJ; Similar to GB:M54884 SP:P21893 PID:147550 PID:887842 GB:U00096; identified by sequence similarity; putative.
    
 
 0.800
ssb
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
    
 
 0.778
VC_1232
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.773
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
       0.702
VC_0334
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 
 0.639
rnhA
Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.608
VC_1235
Sodium/dicarboxylate symporter; Similar to GB:U00096 PID:1742823 PID:1742828 PID:1788024; identified by sequence similarity; putative; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.584
recB
Exodeoxyribonuclease V, 135 kDa subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and [...]
 
   
 0.574
rdgC
Conserved hypothetical protein; May be involved in recombination; Belongs to the RdgC family.
  
     0.548
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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