STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBNicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. (259 aa)    
Predicted Functional Partners:
VC_2042
Histone deacetylase/AcuC/AphA family protein; Similar to SP:P28606 PID:580726 PID:669044 PID:669045; identified by sequence similarity; putative.
    
 
 0.873
VC_A0099
Oxidoreductase, Gfo/Idh/MocA family; Similar to GB:U00096 PID:1742678 PID:1742686 PID:1742694 PID:1742718; identified by sequence similarity; putative.
    
 0.864
VC_0196
ATP-dependent DNA helicase RecQ; Similar to GB:M87049 SP:P15043 GB:M30198 PID:147559 PID:148221; identified by sequence similarity; putative.
  
 
 0.833
VC_1722
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
   0.823
VC_A1048
Oxidoreductase, Gfo/Idh/MocA family; Similar to GB:U00096 SP:P75931 PID:1787307; identified by sequence similarity; putative.
    
 0.803
VC_1153
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
   0.802
VC_1584
ankB protein; Similar to PID:563740 PID:1754534; identified by sequence similarity; putative.
    
 0.802
pta
Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.772
VC_A0208
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the NadD family.
   
 0.763
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
   
 0.749
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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