STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (277 aa)    
Predicted Functional Partners:
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 0.999
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.998
CV_3290
Probable 3-methyl-2-oxobutanoate hydroxymethyltransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0413.
 
  
 0.973
coaX
Probable transcriptional regulator, Bvg acessory factor; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
  
 
 0.972
CV_3423
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx.
   
 0.947
CV_1436
Probable b-alanine-pyruvate transaminase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0161; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.918
cmk
Cytidylate kinase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0283.
      0.912
goaG
4-aminobutyrate transaminase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.902
dfp
DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.895
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0801.
 
   
 0.791
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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