STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsbHProtein-disulfide reductase; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (166 aa)    
Predicted Functional Partners:
dsbA
Thiol:disulfide interchange protein dsbA precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0526.
 
 
 0.994
dsbC
Protein disulfide-isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
 
 
 0.945
dsbD
Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
   
  
 0.845
dsbG
Thiol:disulfide interchange protein DsbG; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
 
 0.808
dsbE
Thioredoxin-related transmembrane protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0526.
  
  
 0.619
hemY
Protein porphyrin biosynthesis; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3071.
 
     0.614
flgG2
Flagellar basal-body rod protein flgG; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1749; Belongs to the flagella basal body rod proteins family.
    
   0.538
flgG1
Flagellar basal-body rod protein FlgG; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1749; Belongs to the flagella basal body rod proteins family.
    
   0.538
hemX
uroporphyrin-III C-methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG2959.
 
     0.536
fumA
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
 
   
 0.533
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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