STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHY_0582Methylaspartate ammonia-lyase; Involved in the methylaspartate cycle. Catalyzes the formation of the alpha,beta-unsaturated bond by the reversible anti elimination of ammonia from L-threo-beta-methylaspartate (L-threo- (2S,3S)-3-methylaspartate) to give mesaconate (By similarity). (415 aa)    
Predicted Functional Partners:
mutE
Methylaspartate mutase, E subunit; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
 
  
 0.980
mamA
Methylaspartate mutase, S subunit; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
 
  
  0.979
CHY_0484
Methylaspartate ammonia-lyase; Involved in the methylaspartate cycle. Catalyzes the formation of the alpha,beta-unsaturated bond by the reversible anti elimination of ammonia from L-threo-beta-methylaspartate (L-threo- (2S,3S)-3-methylaspartate) to give mesaconate. It can also catalyze the amination of fumarate and ethylfumarate, and the deamination of hydroxylamine, hydrazine, methylamine and ethylamine.
  
  
 
0.902
CHY_0583
Conserved hypothetical protein; Identified by similarity to PIR:H85574.
 
     0.880
CHY_0584
Conserved hypothetical protein; Identified by similarity to PIR:G90723.
 
     0.858
CHY_0308
Identified by match to protein family HMM TIGR01319.
 
     0.801
tdk
Thymidine kinase; Identified by similarity to SP:Q03221; match to protein family HMM PF00265.
       0.746
hisA
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Identified by similarity to SP:O35006; match to protein family HMM PF00977; match to protein family HMM TIGR00007.
      
 0.693
CHY_0581
Sigma-54 dependent transcriptional regulator; Identified by match to protein family HMM PF00158; match to protein family HMM PF00989; match to protein family HMM PF02954; match to protein family HMM TIGR00229; match to protein family HMM TIGR01199.
       0.527
CHY_0586
CoA-binding protein; Identified by similarity to GB:BAB59896.1; match to protein family HMM PF02629.
       0.468
Your Current Organism:
Carboxydothermus hydrogenoformans
NCBI taxonomy Id: 246194
Other names: C. hydrogenoformans Z-2901, Carboxydothermus hydrogenoformans Z-2901, Carboxydothermus hydrogenoformans str. Z-2901
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