node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHY_1276 | CHY_1277 | CHY_1276 | CHY_1277 | Putative nicotinate-nucleotide pyrophosphorylase; Identified by similarity to SP:P39666; match to protein family HMM PF01729; match to protein family HMM PF02749; Belongs to the NadC/ModD family. | Probable molybdopterin binding domain protein; Identified by match to protein family HMM PF00994. | 0.984 |
CHY_1276 | CHY_1278 | CHY_1276 | CHY_1278 | Putative nicotinate-nucleotide pyrophosphorylase; Identified by similarity to SP:P39666; match to protein family HMM PF01729; match to protein family HMM PF02749; Belongs to the NadC/ModD family. | Identified by similarity to GP:45682; match to protein family HMM PF01689. | 0.765 |
CHY_1276 | mhpE | CHY_1276 | CHY_1280 | Putative nicotinate-nucleotide pyrophosphorylase; Identified by similarity to SP:P39666; match to protein family HMM PF01729; match to protein family HMM PF02749; Belongs to the NadC/ModD family. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.692 |
CHY_1276 | mhpF | CHY_1276 | CHY_1279 | Putative nicotinate-nucleotide pyrophosphorylase; Identified by similarity to SP:P39666; match to protein family HMM PF01729; match to protein family HMM PF02749; Belongs to the NadC/ModD family. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.750 |
CHY_1277 | CHY_1276 | CHY_1277 | CHY_1276 | Probable molybdopterin binding domain protein; Identified by match to protein family HMM PF00994. | Putative nicotinate-nucleotide pyrophosphorylase; Identified by similarity to SP:P39666; match to protein family HMM PF01729; match to protein family HMM PF02749; Belongs to the NadC/ModD family. | 0.984 |
CHY_1277 | CHY_1278 | CHY_1277 | CHY_1278 | Probable molybdopterin binding domain protein; Identified by match to protein family HMM PF00994. | Identified by similarity to GP:45682; match to protein family HMM PF01689. | 0.810 |
CHY_1277 | CHY_1322 | CHY_1277 | CHY_1322 | Probable molybdopterin binding domain protein; Identified by match to protein family HMM PF00994. | Identified by match to protein family HMM PF01689. | 0.400 |
CHY_1277 | mhpE | CHY_1277 | CHY_1280 | Probable molybdopterin binding domain protein; Identified by match to protein family HMM PF00994. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.728 |
CHY_1277 | mhpF | CHY_1277 | CHY_1279 | Probable molybdopterin binding domain protein; Identified by match to protein family HMM PF00994. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.824 |
CHY_1278 | CHY_1276 | CHY_1278 | CHY_1276 | Identified by similarity to GP:45682; match to protein family HMM PF01689. | Putative nicotinate-nucleotide pyrophosphorylase; Identified by similarity to SP:P39666; match to protein family HMM PF01729; match to protein family HMM PF02749; Belongs to the NadC/ModD family. | 0.765 |
CHY_1278 | CHY_1277 | CHY_1278 | CHY_1277 | Identified by similarity to GP:45682; match to protein family HMM PF01689. | Probable molybdopterin binding domain protein; Identified by match to protein family HMM PF00994. | 0.810 |
CHY_1278 | CHY_1322 | CHY_1278 | CHY_1322 | Identified by similarity to GP:45682; match to protein family HMM PF01689. | Identified by match to protein family HMM PF01689. | 0.900 |
CHY_1278 | mhpE | CHY_1278 | CHY_1280 | Identified by similarity to GP:45682; match to protein family HMM PF01689. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.993 |
CHY_1278 | mhpF | CHY_1278 | CHY_1279 | Identified by similarity to GP:45682; match to protein family HMM PF01689. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.976 |
CHY_1322 | CHY_1277 | CHY_1322 | CHY_1277 | Identified by match to protein family HMM PF01689. | Probable molybdopterin binding domain protein; Identified by match to protein family HMM PF00994. | 0.400 |
CHY_1322 | CHY_1278 | CHY_1322 | CHY_1278 | Identified by match to protein family HMM PF01689. | Identified by similarity to GP:45682; match to protein family HMM PF01689. | 0.900 |
CHY_1322 | mhpE | CHY_1322 | CHY_1280 | Identified by match to protein family HMM PF01689. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.982 |
CHY_1322 | mhpF | CHY_1322 | CHY_1279 | Identified by match to protein family HMM PF01689. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.934 |
ilvC | ilvD | CHY_0519 | CHY_0516 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. | 0.999 |
ilvC | leuB | CHY_0519 | CHY_0524 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.954 |