node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHY_1458 | CHY_1460 | CHY_1458 | CHY_1460 | Conserved hypothetical protein; Identified by similarity to GB:AAM24704.1. | Putative methyltransferase; Identified by similarity to GB:AAM24706.1; match to protein family HMM PF03602; match to protein family HMM TIGR00095. | 0.922 |
CHY_1458 | coaD | CHY_1458 | CHY_1459 | Conserved hypothetical protein; Identified by similarity to GB:AAM24704.1. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.862 |
CHY_1458 | ispH | CHY_1458 | CHY_1925 | Conserved hypothetical protein; Identified by similarity to GB:AAM24704.1. | Hydroxymethylbutenyl pyrophosphate reductase/ribosomal protein S1; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.451 |
CHY_1460 | CHY_1458 | CHY_1460 | CHY_1458 | Putative methyltransferase; Identified by similarity to GB:AAM24706.1; match to protein family HMM PF03602; match to protein family HMM TIGR00095. | Conserved hypothetical protein; Identified by similarity to GB:AAM24704.1. | 0.922 |
CHY_1460 | aroKB | CHY_1460 | CHY_0629 | Putative methyltransferase; Identified by similarity to GB:AAM24706.1; match to protein family HMM PF03602; match to protein family HMM TIGR00095. | Shikimate kinase/3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.520 |
CHY_1460 | coaD | CHY_1460 | CHY_1459 | Putative methyltransferase; Identified by similarity to GB:AAM24706.1; match to protein family HMM PF03602; match to protein family HMM TIGR00095. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.988 |
CHY_1460 | ispH | CHY_1460 | CHY_1925 | Putative methyltransferase; Identified by similarity to GB:AAM24706.1; match to protein family HMM PF03602; match to protein family HMM TIGR00095. | Hydroxymethylbutenyl pyrophosphate reductase/ribosomal protein S1; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.421 |
aroKB | CHY_1460 | CHY_0629 | CHY_1460 | Shikimate kinase/3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Putative methyltransferase; Identified by similarity to GB:AAM24706.1; match to protein family HMM PF03602; match to protein family HMM TIGR00095. | 0.520 |
aroKB | coaBC | CHY_0629 | CHY_1486 | Shikimate kinase/3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.494 |
aroKB | coaD | CHY_0629 | CHY_1459 | Shikimate kinase/3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.751 |
aroKB | coaE | CHY_0629 | CHY_1647 | Shikimate kinase/3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.698 |
aroKB | guaA | CHY_0629 | CHY_1068 | Shikimate kinase/3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.765 |
aroKB | ispH | CHY_0629 | CHY_1925 | Shikimate kinase/3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Hydroxymethylbutenyl pyrophosphate reductase/ribosomal protein S1; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.762 |
aroKB | ribF | CHY_0629 | CHY_1762 | Shikimate kinase/3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Riboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family. | 0.545 |
coaBC | aroKB | CHY_1486 | CHY_0629 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Shikimate kinase/3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.494 |
coaBC | coaD | CHY_1486 | CHY_1459 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.936 |
coaBC | coaX | CHY_1486 | CHY_2370 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Puatative transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.943 |
coaBC | ispH | CHY_1486 | CHY_1925 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hydroxymethylbutenyl pyrophosphate reductase/ribosomal protein S1; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.414 |
coaD | CHY_1458 | CHY_1459 | CHY_1458 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Conserved hypothetical protein; Identified by similarity to GB:AAM24704.1. | 0.862 |
coaD | CHY_1460 | CHY_1459 | CHY_1460 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative methyltransferase; Identified by similarity to GB:AAM24706.1; match to protein family HMM PF03602; match to protein family HMM TIGR00095. | 0.988 |