STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHY_1863Putative multidrug resistance protein; Identified by similarity to SP:P52599; match to protein family HMM PF00529. (364 aa)    
Predicted Functional Partners:
CHY_1864
Drug resistance transporter, EmrB/QacA family; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily.
 
 0.960
CHY_1865
Putative transcriptional regulator; Identified by similarity to GB:CAE34050.1; match to protein family HMM PF01978.
       0.752
CHY_2239
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
  
 0.729
CHY_0090
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
  
 0.705
CHY_2241
Efflux transporter, RND family, MFP subunit; Identified by match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.579
CHY_0871
ABC transporter, permease protein; Identified by similarity to GB:BAC50913.1; match to protein family HMM PF01061.
  
 0.573
hisIE
Histidine biosynthesis bifunctional protein HisIE; Identified by similarity to SP:O34912; match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family.
  
    0.552
CHY_0814
Drug resistance transporter, EmrB/QacA family; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily.
 
 0.534
macB
ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.492
CHY_0089
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
 
 
 0.478
Your Current Organism:
Carboxydothermus hydrogenoformans
NCBI taxonomy Id: 246194
Other names: C. hydrogenoformans Z-2901, Carboxydothermus hydrogenoformans Z-2901, Carboxydothermus hydrogenoformans str. Z-2901
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