node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHY_1233 | fchA1 | CHY_1233 | CHY_0696 | Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family. | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | 0.439 |
CHY_1233 | fchA2 | CHY_1233 | CHY_1879 | Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family. | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | 0.439 |
CHY_1233 | fhs | CHY_1233 | CHY_2385 | Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family. | Formate--tetrahydrofolate ligase; Identified by match to protein family HMM PF01268; Belongs to the formate--tetrahydrofolate ligase family. | 0.810 |
CHY_1233 | folD | CHY_1233 | CHY_1878 | Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family. | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.976 |
CHY_1233 | gcvT | CHY_1233 | CHY_0489 | Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.933 |
CHY_1233 | glyA | CHY_1233 | CHY_2557 | Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.948 |
fchA1 | CHY_1233 | CHY_0696 | CHY_1233 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family. | 0.439 |
fchA1 | fchA2 | CHY_0696 | CHY_1879 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | 0.912 |
fchA1 | fhs | CHY_0696 | CHY_2385 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Formate--tetrahydrofolate ligase; Identified by match to protein family HMM PF01268; Belongs to the formate--tetrahydrofolate ligase family. | 0.945 |
fchA1 | fmt | CHY_0696 | CHY_1483 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.910 |
fchA1 | folD | CHY_0696 | CHY_1878 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.985 |
fchA1 | gcvT | CHY_0696 | CHY_0489 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.921 |
fchA1 | purH | CHY_0696 | CHY_1078 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Bifunctional purine biosynthesis protein PurH; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. | 0.905 |
fchA1 | purN | CHY_0696 | CHY_1077 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.906 |
fchA2 | CHY_1233 | CHY_1879 | CHY_1233 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family. | 0.439 |
fchA2 | fchA1 | CHY_1879 | CHY_0696 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | 0.912 |
fchA2 | fhs | CHY_1879 | CHY_2385 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Formate--tetrahydrofolate ligase; Identified by match to protein family HMM PF01268; Belongs to the formate--tetrahydrofolate ligase family. | 0.945 |
fchA2 | fmt | CHY_1879 | CHY_1483 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.910 |
fchA2 | folD | CHY_1879 | CHY_1878 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.983 |
fchA2 | gcvT | CHY_1879 | CHY_0489 | Methenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.921 |