STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobB2Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (465 aa)    
Predicted Functional Partners:
cobH
precorrin-8X methylmutase; Identified by similarity to GP:15826199; match to protein family HMM PF02570.
 
 0.993
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.953
CHY_0571
Putative cob(I)alamin adenosyltransferase; Identified by similarity to GP:151155; match to protein family HMM PF02572.
  
 
 0.918
cobO
cob(I)alamin adenosyltransferase; Identified by similarity to SP:P13040; match to protein family HMM PF02572; match to protein family HMM TIGR00708.
  
 
 0.918
cobB1
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
  
 
0.917
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 0.902
cbiG
Cobalamin biosynthesis protein CbiG; Identified by similarity to SP:Q05631; match to protein family HMM PF01890.
 
  
 0.896
cobJ
precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466.
 
  
 0.894
cobM
Precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465.
  
 0.881
cbiT
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Identified by match to protein family HMM TIGR02469.
  
 0.878
Your Current Organism:
Carboxydothermus hydrogenoformans
NCBI taxonomy Id: 246194
Other names: C. hydrogenoformans Z-2901, Carboxydothermus hydrogenoformans Z-2901, Carboxydothermus hydrogenoformans str. Z-2901
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