STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menBNaphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (309 aa)    
Predicted Functional Partners:
menD
2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
 
  
 0.985
ABK71168.1
O-succinylbenzoic acid--CoA ligase; Identified by match to protein family HMM PF00501.
 
 
 0.970
ABK75683.1
ComA operon protein 2; Identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369.
 
 
 0.949
menC
O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
 
   
 0.938
ABK69697.1
Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.
 
  
 0.855
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
  
 0.852
ABK73404.1
Oxidoreductase, short-chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.704
ABK73780.1
Conserved hypothetical protein.
  
    0.610
ABK71762.1
O-succinylbenzoate synthase; Identified by match to protein family HMM PF01188; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
   
 0.566
ABK74490.1
Conserved hypothetical protein; Identified by match to protein family HMM TIGR00026.
  
    0.564
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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