STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK73093.1Aminoglycosides/tetracycline-transport integral membrane protein; In association with lipoprotein LprG probably transports triacyglycerides (TAG) across the inner cell membrane into the periplasm; TAG probably regulates lipid metabolism and growth regulation (By similarity). Confers resistance to ethidium bromide, possibly acting as an efflux pump, requires LprG lipoprotein for normal function. Export of ethidium bromide can be complemented by the equivalent operon from M.tuberculosis (lprG- Rv1410c) ; Belongs to the major facilitator superfamily. (560 aa)    
Predicted Functional Partners:
lprG
LprG protein; Probably helps membrane protein MSMEG_3069/MSMEI_2992 (P55) transport triacylglycerides (TAG) across the inner cell membrane into the periplasm and probably ultimately to the outer membrane (By similarity). Required for MSMEG_3069/MSMEI_2992 export activity. Export of ethidium bromide by MSMEG_3069/MSMEI_2992 can be complemented by the equivalent operon from M.tuberculosis (lprG-Rv1410c). Belongs to the LppX/LprAFG lipoprotein family.
 
  
 0.986
ribE
Riboflavin synthase, alpha subunit; Identified by match to protein family HMM PF00677; match to protein family HMM TIGR00187.
  
  
 0.962
ABK73277.1
Identified by similarity to GB:AAK38651.1; match to protein family HMM PF00583.
   
  
 0.820
ABK75968.1
Hypothetical protein; Identified by Glimmer2; putative.
   
  
 0.815
ABK69964.1
Conserved hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands.
   
  
 0.758
ABK71039.1
Conserved hypothetical protein.
  
  
 0.597
ribE-2
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
     
 0.586
ribBA
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.484
mmpl4a
Mmp14a protein; Identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833.
 
 
 0.468
ABK73250.1
MmpL6 protein; Identified by match to protein family HMM PF03176.
 
 
 0.466
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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