node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK73618.1 | ABK74374.1 | MSMEG_3175 | MSMEG_3173 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | L-asparaginase; Identified by match to protein family HMM PF00710. | 0.664 |
ABK73618.1 | lspA | MSMEG_3175 | MSMEG_3174 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | 0.922 |
ABK73618.1 | rarD | MSMEG_3175 | MSMEG_3176 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | RarD protein; Identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688. | 0.833 |
ABK73618.1 | secA | MSMEG_3175 | MSMEG_1881 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.501 |
ABK74374.1 | ABK73618.1 | MSMEG_3173 | MSMEG_3175 | L-asparaginase; Identified by match to protein family HMM PF00710. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.664 |
ABK74374.1 | lspA | MSMEG_3173 | MSMEG_3174 | L-asparaginase; Identified by match to protein family HMM PF00710. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | 0.792 |
ABK74374.1 | rarD | MSMEG_3173 | MSMEG_3176 | L-asparaginase; Identified by match to protein family HMM PF00710. | RarD protein; Identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688. | 0.587 |
lepB | lnt | MSMEG_2441 | MSMEG_3860 | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | 0.461 |
lepB | lspA | MSMEG_2441 | MSMEG_3174 | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | 0.917 |
lepB | secA | MSMEG_2441 | MSMEG_1881 | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.880 |
lgt | lnt | MSMEG_5408 | MSMEG_3860 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | 0.889 |
lgt | lspA | MSMEG_5408 | MSMEG_3174 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | 0.924 |
lgt-2 | lnt | MSMEG_3222 | MSMEG_3860 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | 0.904 |
lgt-2 | lspA | MSMEG_3222 | MSMEG_3174 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | 0.942 |
lnt | lepB | MSMEG_3860 | MSMEG_2441 | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | 0.461 |
lnt | lgt | MSMEG_3860 | MSMEG_5408 | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. | 0.889 |
lnt | lgt-2 | MSMEG_3860 | MSMEG_3222 | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.904 |
lnt | lspA | MSMEG_3860 | MSMEG_3174 | Polyprenol-monophosphomannose synthase Ppm1; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Can transfer a number of fatty acids (C16 and C19, palmitic and probably tuberculostearic acids respectively are shown). Enhances the polyprenol monophosphomannose (PPM) synthase activity of Ppm1 (AC A0QZ12) without itself having PPM synthase catalytic activity. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | 0.965 |
lprG | lspA | MSMEG_3070 | MSMEG_3174 | LprG protein; Probably helps membrane protein MSMEG_3069/MSMEI_2992 (P55) transport triacylglycerides (TAG) across the inner cell membrane into the periplasm and probably ultimately to the outer membrane (By similarity). Required for MSMEG_3069/MSMEI_2992 export activity. Export of ethidium bromide by MSMEG_3069/MSMEI_2992 can be complemented by the equivalent operon from M.tuberculosis (lprG-Rv1410c). Belongs to the LppX/LprAFG lipoprotein family. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | 0.753 |
lspA | ABK73618.1 | MSMEG_3174 | MSMEG_3175 | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.922 |