node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69697.1 | ABK69759.1 | MSMEG_1925 | MSMEG_0029 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.772 |
ABK69697.1 | ABK71866.1 | MSMEG_1925 | MSMEG_5536 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 0.897 |
ABK69697.1 | ABK74300.1 | MSMEG_1925 | MSMEG_2111 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. May play some role in the pathogenicity. | 0.910 |
ABK69697.1 | aroC | MSMEG_1925 | MSMEG_3030 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.940 |
ABK69697.1 | trpA | MSMEG_1925 | MSMEG_3221 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.731 |
ABK69697.1 | trpB | MSMEG_1925 | MSMEG_3220 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.709 |
ABK69697.1 | trpC | MSMEG_1925 | MSMEG_3219 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family. | 0.813 |
ABK69697.1 | trpD | MSMEG_1925 | MSMEG_4258 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.798 |
ABK69697.1 | trpE | MSMEG_1925 | MSMEG_3217 | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.872 |
ABK69759.1 | ABK69697.1 | MSMEG_0029 | MSMEG_1925 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | 0.772 |
ABK69759.1 | ABK71866.1 | MSMEG_0029 | MSMEG_5536 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 0.914 |
ABK69759.1 | ABK74300.1 | MSMEG_0029 | MSMEG_2111 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. May play some role in the pathogenicity. | 0.897 |
ABK69759.1 | aroC | MSMEG_0029 | MSMEG_3030 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.931 |
ABK69759.1 | trpA | MSMEG_0029 | MSMEG_3221 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.976 |
ABK69759.1 | trpB | MSMEG_0029 | MSMEG_3220 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.980 |
ABK69759.1 | trpC | MSMEG_0029 | MSMEG_3219 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family. | 0.995 |
ABK69759.1 | trpD | MSMEG_0029 | MSMEG_4258 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
ABK69759.1 | trpE | MSMEG_0029 | MSMEG_3217 | Anthranilate synthase component 2; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
ABK70498.1 | trpA | MSMEG_3218 | MSMEG_3221 | Trp region conserved hypothetical membrane protein; Identified by match to protein family HMM TIGR02234. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.614 |
ABK70498.1 | trpB | MSMEG_3218 | MSMEG_3220 | Trp region conserved hypothetical membrane protein; Identified by match to protein family HMM TIGR02234. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.616 |