STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mhpBMetapyrocatechase 1; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family. (306 aa)    
Predicted Functional Partners:
mhpA
3-(3-hydroxy-phenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).
 
 
 0.993
ABK74549.1
2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase; Identified by match to protein family HMM PF00561.
 
 
 0.993
ABK75986.1
Hydrolase, alpha/beta fold family protein, putative; Identified by match to protein family HMM PF00561.
 
  
 0.849
ABK70837.1
3-ketosteroid dehydrogenase; Identified by match to protein family HMM PF00890.
 
    0.835
ABK74576.1
2-methylcitrate dehydratase 2; Identified by match to protein family HMM PF03972.
  
  
 0.835
ABK74776.1
3-alpha-hydroxysteroid dehydrogenase.
 
  
 0.829
ABK70954.1
Carboxyvinyl-carboxyphosphonate phosphorylmutase.
   
  
 0.822
ABK75959.1
Carboxyvinyl-carboxyphosphonate phosphorylmutase.
   
  
 0.821
lys1
Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435.
  
  
 0.821
glsA
Thermolabile glutaminase; Identified by match to protein family HMM PF04960; Belongs to the glutaminase family.
   
  
 0.819
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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