STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kstRTranscriptional regulator, TetR family protein; Controls the expression of genes used for utilizing diverse lipids as energy sources. (204 aa)    
Predicted Functional Partners:
kstR2
Transcriptional regulator, TetR family protein; Controls the expression of a small regulon that may play a role in the utilization of cholesterol.
  
  
 0.957
kshA
Rieske [2Fe-2S] domain protein; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A.
 
  
 0.915
ABK76151.1
Putative acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770.
 
  
 0.874
ksdD
3-ketosteroid dehydrogenase; Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids. Is also involved in the formation of 1,4-androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to.
 
  
 0.848
ABK74969.1
enoyl-CoA hydratase; Identified by match to protein family HMM PF00378.
 
  
 0.815
ABK73497.1
MaoC like domain, putative; Identified by match to protein family HMM PF01575.
 
  
 0.807
ABK74901.1
Conserved hypothetical protein.
  
  
 0.799
ABK73895.1
Biphenyl-2,3-diol 1,2-dioxygenase; Identified by match to protein family HMM PF00903.
  
  
 0.790
ABK70448.1
Conserved hypothetical protein; Identified by match to protein family HMM PF01796.
 
    0.787
ABK75352.1
Short chain dehydrogenase; Identified by match to protein family HMM PF00106.
 
  
 0.784
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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