STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK75087.1Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440. (189 aa)    
Predicted Functional Partners:
lfrR
TetR family protein transcriptional repressor LfrR; Represses the transcription of the lfrRA operon by binding directly to the promoter region of lfrR-lfrA. Binds specifically to a 143-bp region upstream of the lfrR gene.
   
  
 0.816
ABK76065.1
Sensor kinase; Identified by match to protein family HMM PF02518; match to protein family HMM PF07730.
  
  
 0.792
ABK71695.1
Putative TetR-family protein transcriptional regulator; Identified by match to protein family HMM PF00440.
  
    0.768
ABK75114.1
Carveol dehydrogenase ((+)-trans-carveol dehydrogenase); Identified by match to protein family HMM PF00106.
  
  
 0.762
ABK74909.1
Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440.
  
    0.762
ABK75369.1
Carveol dehydrogenase; Identified by match to protein family HMM PF00106.
  
  
 0.762
ABK75612.1
Putative RNA methyltransferase; Cg2084; identified by match to protein family HMM PF01938; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
  
  
 0.760
ABK75689.1
Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440.
  
    0.749
ABK73758.1
Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440.
  
     0.734
ethR
Transcriptional regulator, TetR family protein; Involved in the repression of teh monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).
   
  
 0.617
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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