node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK73360.1 | ABK73984.1 | MSMEG_3507 | MSMEG_1375 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. | 0.916 |
ABK73360.1 | derI2 | MSMEG_3507 | MSMEG_6787 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of L-threitol, D- threitol and erythritol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family. | 0.541 |
ABK73360.1 | eno | MSMEG_3507 | MSMEG_5415 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.921 |
ABK73360.1 | fbaA | MSMEG_3507 | MSMEG_0752 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.917 |
ABK73360.1 | gap | MSMEG_3507 | MSMEG_3084 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | Glyceraldehyde-3-phosphate dehydrogenase, type I; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | 0.979 |
ABK73360.1 | gpmA | MSMEG_3507 | MSMEG_0935 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.924 |
ABK73360.1 | pgi | MSMEG_3507 | MSMEG_5541 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | Glucose-6-phosphate isomerase; Identified by similarity to SP:P11537; match to protein family HMM PF00342; Belongs to the GPI family. | 0.936 |
ABK73360.1 | pgk | MSMEG_3507 | MSMEG_3085 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | Phosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. | 0.549 |
ABK73360.1 | pyk | MSMEG_3507 | MSMEG_0154 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.883 |
ABK73360.1 | tpiA-2 | MSMEG_3507 | MSMEG_6785 | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | Triosephosphate isomerase; Catalyzes the isomerization of L-erythrulose-1P to D- erythrulose-4P. Involved in the degradation pathway of L-threitol, that allows M.smegmatis to grow on this compound as the sole carbon source. Belongs to the triosephosphate isomerase family. | 0.861 |
ABK73984.1 | ABK73360.1 | MSMEG_1375 | MSMEG_3507 | Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | 0.916 |
ABK73984.1 | eno | MSMEG_1375 | MSMEG_5415 | Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.944 |
ABK73984.1 | fbaA | MSMEG_1375 | MSMEG_0752 | Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.914 |
ABK73984.1 | gap | MSMEG_1375 | MSMEG_3084 | Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. | Glyceraldehyde-3-phosphate dehydrogenase, type I; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | 0.970 |
ABK73984.1 | gpmA | MSMEG_1375 | MSMEG_0935 | Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.897 |
ABK73984.1 | pgi | MSMEG_1375 | MSMEG_5541 | Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. | Glucose-6-phosphate isomerase; Identified by similarity to SP:P11537; match to protein family HMM PF00342; Belongs to the GPI family. | 0.931 |
ABK73984.1 | pgk | MSMEG_1375 | MSMEG_3085 | Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. | Phosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. | 0.792 |
ABK73984.1 | pyk | MSMEG_1375 | MSMEG_0154 | Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.903 |
ABK73984.1 | tpiA-2 | MSMEG_1375 | MSMEG_6785 | Tagatose-1,6-bisphosphate aldolase GatY; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167. | Triosephosphate isomerase; Catalyzes the isomerization of L-erythrulose-1P to D- erythrulose-4P. Involved in the degradation pathway of L-threitol, that allows M.smegmatis to grow on this compound as the sole carbon source. Belongs to the triosephosphate isomerase family. | 0.795 |
derI2 | ABK73360.1 | MSMEG_6787 | MSMEG_3507 | Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of L-threitol, D- threitol and erythritol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family. | Fructose-bisphosphate aldolase class-I; Identified by match to protein family HMM PF00274. | 0.541 |