node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69654.1 | ABK75692.1 | MSMEG_1363 | MSMEG_6869 | Glucokinase; Identified by match to protein family HMM PF00480. | Identified by match to protein family HMM PF00480. | 0.929 |
ABK69654.1 | ino1 | MSMEG_1363 | MSMEG_6904 | Glucokinase; Identified by match to protein family HMM PF00480. | Myo-inositol-1-phosphate synthase; Catalyzes the conversion of glucose 6-phosphate to 1D-myo- inositol 3-phosphate; Belongs to the myo-inositol 1-phosphate synthase family. | 0.907 |
ABK69654.1 | pgm | MSMEG_1363 | MSMEG_2136 | Glucokinase; Identified by match to protein family HMM PF00480. | Phosphoglucomutase, alpha-D-glucose phosphate-specific; Identified by similarity to SP:P36938; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; match to protein family HMM TIGR01132. | 0.935 |
ABK69903.1 | ABK72681.1 | MSMEG_3116 | MSMEG_2762 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | 0.916 |
ABK69903.1 | impA | MSMEG_3116 | MSMEG_3210 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Inositol monophosphate phosphatase; Catalyzes the dephosphorylation of inositol 1-phosphate (I-1- P) to yield free myo-inositol, a key metabolite in mycobacteria. | 0.933 |
ABK69903.1 | ino1 | MSMEG_3116 | MSMEG_6904 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Myo-inositol-1-phosphate synthase; Catalyzes the conversion of glucose 6-phosphate to 1D-myo- inositol 3-phosphate; Belongs to the myo-inositol 1-phosphate synthase family. | 0.972 |
ABK69903.1 | pgsA-2 | MSMEG_3116 | MSMEG_2933 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Phosphatidylinositol synthase; Catalyzes the conjugation of the 1'-hydroxyl group of D-myo- inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid for mycobacteria required for formation of their cell wall. Is essential to the survival of M.smegmatis. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.743 |
ABK71430.1 | ABK73510.1 | MSMEG_6906 | MSMEG_6903 | Putative hydrolase; Identified by match to protein family HMM PF00561. | Transcriptional regulator, PadR family protein; Identified by match to protein family HMM PF03551. | 0.734 |
ABK71430.1 | ino1 | MSMEG_6906 | MSMEG_6904 | Putative hydrolase; Identified by match to protein family HMM PF00561. | Myo-inositol-1-phosphate synthase; Catalyzes the conversion of glucose 6-phosphate to 1D-myo- inositol 3-phosphate; Belongs to the myo-inositol 1-phosphate synthase family. | 0.789 |
ABK72681.1 | ABK69903.1 | MSMEG_2762 | MSMEG_3116 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | 0.916 |
ABK72681.1 | impA | MSMEG_2762 | MSMEG_3210 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Inositol monophosphate phosphatase; Catalyzes the dephosphorylation of inositol 1-phosphate (I-1- P) to yield free myo-inositol, a key metabolite in mycobacteria. | 0.932 |
ABK72681.1 | ino1 | MSMEG_2762 | MSMEG_6904 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Myo-inositol-1-phosphate synthase; Catalyzes the conversion of glucose 6-phosphate to 1D-myo- inositol 3-phosphate; Belongs to the myo-inositol 1-phosphate synthase family. | 0.972 |
ABK72681.1 | pgsA-2 | MSMEG_2762 | MSMEG_2933 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Phosphatidylinositol synthase; Catalyzes the conjugation of the 1'-hydroxyl group of D-myo- inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid for mycobacteria required for formation of their cell wall. Is essential to the survival of M.smegmatis. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.740 |
ABK73510.1 | ABK71430.1 | MSMEG_6903 | MSMEG_6906 | Transcriptional regulator, PadR family protein; Identified by match to protein family HMM PF03551. | Putative hydrolase; Identified by match to protein family HMM PF00561. | 0.734 |
ABK73510.1 | ino1 | MSMEG_6903 | MSMEG_6904 | Transcriptional regulator, PadR family protein; Identified by match to protein family HMM PF03551. | Myo-inositol-1-phosphate synthase; Catalyzes the conversion of glucose 6-phosphate to 1D-myo- inositol 3-phosphate; Belongs to the myo-inositol 1-phosphate synthase family. | 0.894 |
ABK75692.1 | ABK69654.1 | MSMEG_6869 | MSMEG_1363 | Identified by match to protein family HMM PF00480. | Glucokinase; Identified by match to protein family HMM PF00480. | 0.929 |
ABK75692.1 | ino1 | MSMEG_6869 | MSMEG_6904 | Identified by match to protein family HMM PF00480. | Myo-inositol-1-phosphate synthase; Catalyzes the conversion of glucose 6-phosphate to 1D-myo- inositol 3-phosphate; Belongs to the myo-inositol 1-phosphate synthase family. | 0.905 |
ABK75692.1 | pgm | MSMEG_6869 | MSMEG_2136 | Identified by match to protein family HMM PF00480. | Phosphoglucomutase, alpha-D-glucose phosphate-specific; Identified by similarity to SP:P36938; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; match to protein family HMM TIGR01132. | 0.911 |
impA | ABK69903.1 | MSMEG_3210 | MSMEG_3116 | Inositol monophosphate phosphatase; Catalyzes the dephosphorylation of inositol 1-phosphate (I-1- P) to yield free myo-inositol, a key metabolite in mycobacteria. | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | 0.933 |
impA | ABK72681.1 | MSMEG_3210 | MSMEG_2762 | Inositol monophosphate phosphatase; Catalyzes the dephosphorylation of inositol 1-phosphate (I-1- P) to yield free myo-inositol, a key metabolite in mycobacteria. | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | 0.932 |