node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70644.1 | eccE1 | MSMEG_0081 | MSMEG_0082 | Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family. | Conserved hypothetical protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in at least a donor strain. | 0.843 |
ABK70644.1 | mycP1 | MSMEG_0081 | MSMEG_0083 | Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family. | Membrane-anchored mycosin mycp1; May play a dual role in regulation of ESX-1 secretion and virulence. Acts as a protease that cleaves EspB. Belongs to the peptidase S8 family. | 0.786 |
ABK73967.1 | ABK74495.1 | MSMEG_1534 | MSMEG_0061 | Probable conserved membrane protein; Identified by match to protein family HMM PF05108. | Identified by match to protein family HMM PF01580. | 0.842 |
ABK73967.1 | eccCb1 | MSMEG_1534 | MSMEG_0062 | Probable conserved membrane protein; Identified by match to protein family HMM PF05108. | Ftsk/spoiiie family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains. | 0.756 |
ABK73967.1 | eccE1 | MSMEG_1534 | MSMEG_0082 | Probable conserved membrane protein; Identified by match to protein family HMM PF05108. | Conserved hypothetical protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in at least a donor strain. | 0.576 |
ABK73967.1 | mycP1 | MSMEG_1534 | MSMEG_0083 | Probable conserved membrane protein; Identified by match to protein family HMM PF05108. | Membrane-anchored mycosin mycp1; May play a dual role in regulation of ESX-1 secretion and virulence. Acts as a protease that cleaves EspB. Belongs to the peptidase S8 family. | 0.809 |
ABK74495.1 | ABK73967.1 | MSMEG_0061 | MSMEG_1534 | Identified by match to protein family HMM PF01580. | Probable conserved membrane protein; Identified by match to protein family HMM PF05108. | 0.842 |
ABK74495.1 | eccA1 | MSMEG_0061 | MSMEG_0059 | Identified by match to protein family HMM PF01580. | ATPase, AAA family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains. EccA1 exhibits ATPase activity and may provide energy for the export of ESX-1 substrates (By similarity). | 0.919 |
ABK74495.1 | eccB1 | MSMEG_0061 | MSMEG_0060 | Identified by match to protein family HMM PF01580. | Conserved hypothetical protein; An ATPase (shown for residues 72-479). Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains ; Belongs to the EccB family. | 0.980 |
ABK74495.1 | eccB3 | MSMEG_0061 | MSMEG_0616 | Identified by match to protein family HMM PF01580. | Conserved hypothetical protein; An ATPase (By similarity). Part of the ESX-3 specialized secretion system, which is required for siderophore-mediated iron acquisition and for the secretion of EsxH and EsxG. | 0.663 |
ABK74495.1 | eccCb1 | MSMEG_0061 | MSMEG_0062 | Identified by match to protein family HMM PF01580. | Ftsk/spoiiie family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains. | 0.990 |
ABK74495.1 | eccE1 | MSMEG_0061 | MSMEG_0082 | Identified by match to protein family HMM PF01580. | Conserved hypothetical protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in at least a donor strain. | 0.875 |
ABK74495.1 | espE | MSMEG_0061 | MSMEG_0055 | Identified by match to protein family HMM PF01580. | Hypothetical protein; Identified by Glimmer2; putative. | 0.846 |
ABK74495.1 | esxB | MSMEG_0061 | MSMEG_0065 | Identified by match to protein family HMM PF01580. | Conserved hypothetical protein; An exported protein. Plays a role in DNA conjugation, in at least a donor strain ; Belongs to the WXG100 family. CFP-10 subfamily. | 0.729 |
ABK74495.1 | mycP1 | MSMEG_0061 | MSMEG_0083 | Identified by match to protein family HMM PF01580. | Membrane-anchored mycosin mycp1; May play a dual role in regulation of ESX-1 secretion and virulence. Acts as a protease that cleaves EspB. Belongs to the peptidase S8 family. | 0.823 |
eccA1 | ABK74495.1 | MSMEG_0059 | MSMEG_0061 | ATPase, AAA family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains. EccA1 exhibits ATPase activity and may provide energy for the export of ESX-1 substrates (By similarity). | Identified by match to protein family HMM PF01580. | 0.919 |
eccA1 | eccB1 | MSMEG_0059 | MSMEG_0060 | ATPase, AAA family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains. EccA1 exhibits ATPase activity and may provide energy for the export of ESX-1 substrates (By similarity). | Conserved hypothetical protein; An ATPase (shown for residues 72-479). Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains ; Belongs to the EccB family. | 0.985 |
eccA1 | eccB3 | MSMEG_0059 | MSMEG_0616 | ATPase, AAA family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains. EccA1 exhibits ATPase activity and may provide energy for the export of ESX-1 substrates (By similarity). | Conserved hypothetical protein; An ATPase (By similarity). Part of the ESX-3 specialized secretion system, which is required for siderophore-mediated iron acquisition and for the secretion of EsxH and EsxG. | 0.636 |
eccA1 | eccCb1 | MSMEG_0059 | MSMEG_0062 | ATPase, AAA family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains. EccA1 exhibits ATPase activity and may provide energy for the export of ESX-1 substrates (By similarity). | Ftsk/spoiiie family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains. | 0.966 |
eccA1 | eccE1 | MSMEG_0059 | MSMEG_0082 | ATPase, AAA family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains. EccA1 exhibits ATPase activity and may provide energy for the export of ESX-1 substrates (By similarity). | Conserved hypothetical protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in at least a donor strain. | 0.853 |